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          Deep Dive: Berlin


          Berlin is both the capital and     Hospital, and more than 40 non-      Finally, the capital region also
          the largest city in Germany, with   university research institutions,   provides established structures
          more than 3.6M inhabitants         at least 17 of which focus on the   for life science companies (34
          at the end of 2019. While the      life sciences.                     large life science companies,
          German industry primarily                                             255 biotech companies, and
          resides in southern parts of       In detail, Berlin’s particular     332 medical technology
                                                                                          15
          the country, many German and       strengths lie in public sector     companies) . Among the
          international companies are        R&D spending at 1.5 times of       bioinformatics ventures of the
          headquartered in Berlin. The       the German and 1.8 times of the    German capital region, we find
          region has one of the highest      European average and non-R&D       Genetek Biopharma and Biotx.ai.
          proportions of SMEs: 181,581       innovation spending. This is       Genetek Biopharma manufactures
          SMEs compared to 633               reflected in excellent public-     genetic diagnostic kits based
          companies with more than 250       private co-publications, at 137%   on QF-PCR technique – for
                   14
          employees .                        of the German and 169% of the      detection of genetic diseases
                                                             13
                                             European average .                 and chromosomal anomalies
          According to the ‘Regional                                            and human DNA profiling
          Innovation Scoreboard 2019’,       Ventures in the domain typically   kits used in forensics and
          Berlin is characterised as         reside in one of nine current      kinship issues. Biotx.ai delivers
          ‘Innovation Leader +’, and has     science parks, with many more      predictive biomarkers as a basis
          been so classified since 2012.     under development at the time      for decision support in precision
                                             of this report. In comparison to   medicine. The venture applies
          In recent years, the city has      Cambridge, the ecosystem has       machine learning techniques to
          become a well-known centre for     seen fewer companies with large    automatically select hypotheses
          technology-oriented ventures,      scale exits in the past. Thus      from life science data and
          particularly in e-commerce,        even though more and more          eventually diagnose previously
          financial technologies, data       capital flows into the region      undiagnosed patients using
          sciences and analytics. The        by venture capital funds, early-   polygenic analysis.
          region provides broad access       stage and growth investment are
          to scientific insights and highly-  heavily complemented by public
          trained talent at 11 public        investors. This being said, early-
          universities, including Europe’s   stage venture rounds are larger
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          largest university hospital,       than the global average .
          Charité University Medicine

          13  Regional Innovation Scoreboard, Berlin – Internal Market, Industry, Entrepreneurship and SMEs – European Commission. https://ec.europa.eu/growth/tools-databases/
            regional-innovation-monitor/base-profile/berlin (visited in 2019).
          14  Startup Genome – Berlin. https://startupgenome.com/ecosystems/berlin.
          15  Life Sciences Report 2019/2020 – Berlin Partner for Business and Technology  https://www.berlin-partner.de/fileadmin/user_upload/01_chefredaktion/02_pdf/
            publikationen/Life-Sciences-Report_en.pdf (2020).


                                                                                            Berlin
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