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            Open data enable innovation

            in the bioinformatics industry


            Research data is a major asset for life sciences      “
            industry 2,3,4 . Exploiting these data drives
            development within health, agriculture and
            biotechnology sectors, thereby leading to economic
            and societal benefits. For example, to accelerate
                                                                     ‘The more freely available data that is
            drug development, produce efficient washing
                                                                     compatible with other data, the better for us.
            powder, and even design better feed for livestock
                                                                     Without open data resources, large companies,
            and pets.
                                                                     such as pharmaceuticals, would be hampered
                                                                     in their work but would not cease to exist. In
            Such innovative life sciences projects require the
            essential use of open data, open-source software         contrast, small and medium-sized enterprises,
            and common standards. Together, open resources           as well as the startups, would be severely
            allow industry, academia and the wider community         impacted as in many cases their business models
            to create novel services and products.                   are dependent on the availability of open data
                                                                     resources.’
            For today’s digital life sciences, data standards
            and data quality are major bottlenecks for data
                                                                                                   Hans Garritzen
            accessibility and data sustainability, thereby
                                                                                           Sales Director, Medisapiens
            essential enablers of effective data utilisation.
            Research infrastructures, such as ELIXIR, ensure
            that life science innovators and researchers globally    ‘I think Europe, by investing in that framework
            can utilise open data. They facilitate access to open    [ELIXIR], is doing the right thing to support the
            resources such as databases, repositories, software      long term sustainability of the Life Sciences
            tools, registries, compute and cloud resources, while    knowledge economy. Imagine if all the data
            promoting standards and enabling collaboration           resources that are freely available today would
                                               5
            through training and networking events .                 disappear from tomorrow. It would be tough
                                                                     for the life sciences companies to sustain their
            This report sheds light on the importance of
                                                                     innovation. They would have to work really,
            continued access to open data and related
                                                                     really hard and spend a large portion of their
            resources, along with their underpinning
                                                                     Research and Development (R&D) spending on
            infrastructures that contribute to a thriving life
                                                                     replacing that common good.’
            science ecosystem.
            We showcase the growing European bioinformatics                                      Abel Ureta-Vidal
            industry and its local environment, and demonstrate
                                                                             Co-founder & Chief Data Officer at Sofi Health,
            the importance of long-term investment in digital                       Investment director at CMS Ventures
            research infrastructures as bedrocks for innovation.

                                                                     ‘Open data is absolutely crucial for us. As soon
                                                                     as we want to explore new ways of finding
                                                                     molecules, because this is our business, we first
                                                                     need to have some proof of concept to make
                                                                     sure that we are heading in the right direction.
                                                                     For that, we are actually heavily reliant on open
            2  Beagrie, N. & Houghton, J. The Value and Impact of the European   data.’
              Bioinformatics Institute Full Report. http://www.beagrie.com/EBI-impact-
              report.pdfandhttp://www.beagrie.com/EBI-impact-summary.pdf (2016).
            3  Jefferson, O. A. et al. Mapping the global influence of published research on
              industry and innovation. Nat. Biotechnol. 36, 31–39 (2018).
            4  Westbrook, J. D., Soskind, R., Hudson, B. P. & Burley, S. K. Impact of the          Florent Villiers
              Protein Data Bank on antineoplastic approvals. Drug Discovery Today vol. 25   Lab Leader for Biochemistry & Data Science, Bayer
              837–850 (2020).
            5  Garcia, P. R. et al. Public data resources as a business model for SMEs. The
              Role of Public Bioinformatics Infrastructure in supporting innovation in the
              life sciences  [version 1; not peer reviewed]. F1000Research vol. 7 https://doi.
              org/10.7490/f1000research.1115445.1 (2018)                                                           “
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