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             Value chain for   data analysis  Selection  Integration and   Transformation  Mining  Interpretation
                                           processing








                                                           Custom Full Service


                  High Quality Data Service
               Business Model  Vocabulary Generation     Configurable Model






                                                                                          Care Service


                                                          Workflow as a Service



            Figure 4. Appropriation strategies of companies along the data analysis value chain



            These openly available resources are mostly           Depending on what stage(s) a company operates
            combined with proprietary resources created           along the value chain, it can employ different
                                                                                        18
            by bioinformatics ventures themselves or their        appropriation strategies . A firm can either
            clients in the private sector. Outputs of those       focus on one or more core activities or include
            companies can vary considerably and range from        the whole value chain in its business strategy.
            drug discovery or diagnostic tests, to shaping new    Particularly at early stages, our survey has shown
            technology solutions or even domestic products        that bioinformatics ventures tend to provide a full-
            such as washing powders.                              service model for clients on a custom and hardly
                                                                  scalable basis. The majority of mature ventures
            With more open and proprietary life science data      rely on technology to either provide a product at a
            resources available, the bioinformatics industry      particular stage, for instance, to provide access to
            has brought forth companies on multiple stages of     curated repositories of open and proprietary data,
            the value chain. Figure 4 provides an overview of     or generate tools for creating ontologies that will
            the value chain of businesses making use of open      integrate new data resources and answer specific
            life science resources:                               research questions.

            1.   Collecting, selecting, and providing data        To provide a scalable product along the entire
                 resources.                                       value chain, some companies created platforms
                                                                  and private infrastructures that help customise
            2.   Integrating data and pre-processing these
                                                                  otherwise automated workflows to process raw
                 resources for later use either by the company
                                                                  data into visualisations and insights.
                 itself or its customers.
            3.   Transforming data into models such as
                 vocabularies or ontologies.

            4.   Enabling customers to create their own
                 insights from these models through mining.

            5.   Providing interpretations from the data on
                 behalf of a client, for example in the form of
                 reports.



            18  Rothe, H., Jarvenpaa, S. & Penninger, A. How do entrepreneurial firms appropriate value in bio data infrastructures: an exploratory qualitative study. Res. Pap. (2019).
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