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          Spotlight on


          open data





          Open data resources are           resource stands out as most
          essential for today’s life science   important). Figure 6 shows how
          community in both academia and    ventures combine data from
          industry. They act as archives of   different databases.
          experimental research data, inform
          future research studies’ direction,   They combine open data
          and help link and bring together   resources, often with proprietary
          a vast wealth of interoperable    information, to create value for
          information.                      customers. In doing so, ventures
                                            combine open data resources,
          Many new databases are essential   often with proprietary information.
          to the broad research community,   To enable new insights to be
          but only a few have a sustained   garnered, or to facilitate a diverse                  no growth
          funding model, as highlighted in a   range of customers to gain new           growth of turnover and
          recent study. In an 18-year period,   knowledge, an assortment of                       emplyees
          more than 60% of life science     data needs to be connected and
          research databases ceased to exist,   analysed. We, therefore, found that
          and a further 14% were no longer   companies that grew more rapidly
                 19
          updated .                         were among those who used many
                                            different resources in combination                         40
          Research infrastructures such     (Figure 5).
          as ELIXIR work to increase the
          long-term sustainability of their
          resources and carry out targeted
          actions so that these feed into                                                              30
          innovation and discovery in the
          data-driven life science sector. Our
          study highlighted the significance
          of open data resources, particularly                                                             Companies in sample [%]
          for small and medium-sized life                                                              20
          science companies, exemplified by
          73% of respondents indicating that
          data resources with information on
          rare diseases (e.g. from Orphanet)
                                                                                                       10
          are important to the business.
          Repositories holding information
          on scientific publications present
          another good example (e.g. from
          EuropePMC) or human genomics                                                                 0
          data (e.g. from EGA). 84% and
          71% of respondents highlighted              0           1-5          6-10         >10
          the importance of open data their          Number of different data repository types used by venture
          business operations.
                                              Figure 5. Percentage of companies reporting either growth of turnover and number
          Interestingly all companies in the
                                              of employees or no change, related to the number of open data repositories used by
          survey indicatezzwas relevant
                                              a company.
          to the business (no individual

          19  zAttwood, T. K., Agit, B. & Ellis, L. B. M. Longevity of Biological Databases. EMBnet.journal 21, (2015).
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